Frontal-striatum dysfunction during reward processing: Relationships to amotivation in schizophrenia.
نویسندگان
چکیده
منابع مشابه
Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia.
Amotivation and reward-processing deficits have long been described in patients with schizophrenia and considered large contributors to patients' inability to integrate well in society. No effective treatments exist for these symptoms, partly because the neuromechanisms mediating such symptoms are poorly understood. Here, we propose a translational neuroscientific approach that can be used to a...
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PURPOSE OF REVIEW This article reviews the recent literature on reward processing dysfunction in major depression (MDD), bipolar disorder and schizophrenia, with a focus on approach motivation, reward learning and reward-based decision-making. RECENT FINDINGS Emerging evidence indicates the presence of reward processing abnormalities across all three disorders, supporting a transdiagnostic ap...
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Anhedonia, the inability to feel pleasure, and amotivation, the lack of motivation, are two prominent negative symptoms of schizophrenia, which contribute to the poor social and occupational behaviors in the patients. Recently growing evidence shows that anhedonia and amotivation are tied together, but have distinct neural correlates. It is important to note that both of these symptoms may deri...
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ژورنال
عنوان ژورنال: Journal of Abnormal Psychology
سال: 2016
ISSN: 1939-1846,0021-843X
DOI: 10.1037/abn0000137